Lantana camara is a herb having antimicrobial, antidiabetic, hepatotoxic properties and is used in traditional system of medicine. Extract from root was prepared and different concentrations of this extract were examined for their activities against microbial agents and for their tolerance by specific cell culture. The cell culture was challenged with different doses of virus and the cultures were observed whether they can withstand or resist the challenge dose when treated with extract or whether the cell culture is capable of resisting the invasion or inhibiting the multiplication of the virus. Thereby, preventing the virus infection the different dilutions of extract did show a very low level of protection when challenged with a low dose of virus. The extract failed to protect the cell cultures with a high dose of virus challenge (100TCID50). In this investigation, the polio virus Type I, RNA virus was used as a challenge virus and the result indicated that the plant extract of root offered slight protection when the cells were treated with 100-200 µg/ml of the extract.
Loading....